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Research networks

Collaborative projects

Large collaborative projects are a hallmark of each faculty's profile and research strength.  Within the framework of various associations and networks, the Faculty of Medicine cooperates with scientists from different departments of the Heinrich Heine University, especially with the Faculty of Mathematics and Natural Sciences, with research institutions outside the HHU and with other universities.  This shows that traditional subject and discipline boundaries are increasingly permeable and create considerable potential for innovation at the subject boundaries. 

All currently funded projects with a total volume of 1.5 million euros or more with a spokesperson or coordination or representation of these functions at HHU are listed here.


Master switches in cardiac ischemia

Speaker: Prof. Dr. Jens Fischer, Institute of Pharmacology and Clinical Pharmacology
Deputy Speaker: Prof. Dr. med. Malte Kelm, Department of Cardiology, Pneumology and Angiology
Duration: since 2015

Aortic Disease

Speaker: Prof. Dr. Georg Nickenig (Uni Bonn)
Deputy spokesperson: Prof. Dr. Malte Kelm (HHU, Department of Cardiology, Pneumology & Angiology)
Duration: since 2019

Identity and dynamics of membrane systems - from molecules to cellular functions

With the participation of medical institutions
Spokesperson: Prof. Dr. Lutz Schmitt (HHU, Math.-Nat. Faculty)
Deputy spokesperson: Prof. Dr. Andreas Weber (Math.-Nat. Faculty)
Duration: since 2016

Impact of genotoxins on the differentiation efficacy of murine and human stem and progenitor cells and functional competence of thereof derived differentiated progeny

Spokesperson: Prof. Dr. Dr. Gerhard Fritz HHU, Institute of Toxicology)
Deputy spokesperson: Prof. Dr. James Adjaye (Institute of Stem Cell Research and Regenerative Medicine)
Duration: since 2021

In vivo investigations towards the early development of type 2 diabetes

Spokesperson: Prof. Dr. Hadid Al-Hasani (DDZ, Institute of Clinical Biochemistry and Pathobiochemistry)
Deputy spokesperson: Prof. Dr. Regina Ensenauer (HHU, Department of General Paediatrics, Neonatology and Paediatric Cardiology)
Duration: since 2020

Natural products and natural product analogs against therapy-resistant tumors and microorganisms: new lead structures and modes of action

Faculty of Mathematics and Natural Sciences, in cooperation with the Faculty of Medicine
Spokesperson: Prof. Dr. Holger Gohlke (Math.-Nat. Faculty)
Deputy spokesperson: 
Prof. Dr. Sebastian Wesselborg (Faculty of Medicine)
Prof. Dr. Rainer Kalscheuer (Faculty of Math.-Nat.)
Duration: since 2016 

Intra- and interorgan communication of the cardiovascular system

Prof. Dr. rer. nat. Axel Gödecke
Institute of Cardiovascular Physiology
Duration: since 2013 
Partner / USA: University of Virginia

NORMAL#CRAZY. Contemporary history of an eroding difference

Speaker: Prof. Dr. Heiner Fangerau (HHU, Institute of History, Theory and Ethics of Medicine)
Deputy. Speaker: Prof. Dr. Volker Hess (Charité Berlin, Institute of History and Ethics in Medicine)
Duration: since 2021

Synapses under stress: acute changes due to lack of energy supply at glutamatergic synapses

Participation of the Faculty of Medicine
Spokesperson: Prof. Dr. Christine Rose (HHU, Math.-Nat. Faculty)
Jun. Prof. Dr. Nadine Erlenhardt (Institute of Neuro- and Sensory Physiology) 
Subproject 7: "LifecycleofAMPA-receptorsunderacute metabolic stress".
Prof. Dr. Alessandro Prigione (Department of General Paediatrics, Neonatology and Paediatric Cardiology) and Dr. Ruchika Anand (Institute of Biochemistry and Molecular Biology I)
Subproject 8: "Mitochondrial remodelling in human neurons, astrocytes and brain organoids under metabolic failure".
Duration: since 2019

Institutional contexts, health and health inequalities among young people. A life phase approach

In cooperation
Spokesperson: Prof. Dr. Matthias Richter (Martin Luther University Halle-Wittenberg)
Prof. Dr. Nico Dragano (HHU, Institute of Medical Sociology) & Prof. Dr. Claudia Pischke (Institute of Medical Sociology)
Sub-project 4: "Transitions from school to work and health inequalities among young adults".
Duration: since 2019

Federal / State / Foundations

Beyond Covid 19: A university network to characterise health and psychosocial late effects after convalescence from a SARS-CoV-2 infection in NRW

Spokesperson: Prof. Dr. Tom Lüdde
Department of Gastroenterology, Hepatology and Infectiology
MKW NRW: 4.599.655 euros
Duration: 48 months

CARE - Computer-Assisted Risk Evaluation in the Early Diagnosis of Psychotic Disorders

Spokesperson: Prof. Dr. Eva Meisenzahl-Lechner
Clinic and Polyclinic of Psychiatry and Psychotherapy, LVR Clinic
GbA: 9.458.050 euros
Duration: 36 months


Prof. Dr Tom Lüdde
Department of Gastroenterology, Hepatology and Infectiology
Federal government: 1.932.500 euros
Duration: 36 months (01.10.2020 - 30.09.2023)

DETECT CTC: Application of liquid biopsies to decipher therapy resistance mechanisms and develop adaptive treatment strategies in metastatic breast cancer

Prof. Dr. Tanja Fehm
Department of Gynaecology and Obstetrics
German Cancer Aid e.V.: 2.000.000 euros
Duration: since 14.02.2022

GIGA FOR HEALTH: 5G Medical Campus.NRW

Speaker: Prof. Dr. Dr. Frank Schneider
Board of Directors
MWIDE.NRW: 7.331.413 euros
Duration: 26 months

Multi-Omics Data Science (MODS)

Prof. Dr Tobias Marschall
Institute of Medical Biometry and Bioinformatics
State of NRW: 2.749.558 euros
Duration: 36 months (01.11.2021 - 31.10.2024)

PRO-P - Influence of electronic Patient Reported Outcomes (ePROMS) in surgical therapy of prostate carcinoma on the postoperative course

Prof. Dr Peter Albers
Clinic of Urology
Federal Government / G-BA: 2.393.100 euros
Duration: 36 months (01.04.2022 - 31.03.2025)

PSY-KOMO - Comorbid somatic illnesses in patients with severe mental disorders to reduce somatic comorbidity and increased mortality

Spokesperson: Prof. Dr. Dr. Frank Schneider
Institute of Health Services Research
GbA (Federal Government): 8.789.680 euros
Duration: 36 months

Reconvalescent plasma early in SARS-CoV-2 Q-PCR positive high risk individuals - RES-Q HR trial

Spokesperson: Prof. Dr. Tom Lüdde
Department of Gastroenterology, Hepatology and Infectiology
BMG: 10.566.644 euros
Duration: 16 months

European Commission

Human Brain Project

Prof. Dr. Katrin Amunts (Scientific Research Director),
Prof. Dr. Dr. Svenja Caspers, Prof. Dr. Simon Eickhoff
EU: 1.601.285 euros
Duration: 35 months (01.04.2020. - 28.02.2023)


Prof. Dr. Tom Lüdde
Department of Gastroenterology, Hepatology and Infectiology
EU: 1.825.340 euros
Duration: 60 months (01.11.2018 - 31.10.2023)

Recovery Assistance for Cohension and the Territories of Europe (REACT-EU) "Digitalisation in Clinical Medicine and Health Research (OnkoHPC)"

Prof. Dr. Tobias Marschall
Institute of Medical Biometry and Bioinformatics
EU: 1.507.730 euros
Duration: 12 months

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