Third-party funded projects 2022, 3rd quarter

Prof. Dr. Alexander Assmann
Clinic of Cardiac Surgery
Effects of extracorporeal circulation on the heart-brain axis: quantification of perfusion by 4D-MRI
BMBF: 28,361 euros
Duration: 12 months

Dr. Kathrin Becker
Department of Orthodontics
Effects of surface modification and loading time of orthodontic implants on implant migration in bone, and analysis of associated microangiogenetic patterns and osteocytic gene expression
DFG: 260,509 euros
Duration: 36 months

Prof. Dr. Freia De Bock
Department of General Paediatrics, Neonatology and Paediatric Cardiology
PICAR - Patient Journeys of Children with Chronic Diseases: Cross-indication analysis and recommendations for integrated care
Federal G-BA: 1,507,690 euros
Duration: 36 months

Prof. Dr. Ulrike Dinger-Ehrenthal
Clinical Institute of Psychosomatic Medicine and Psychotherapy Integrative Interpersonal Therapy for Depression after Stroke - INID- PILOT
DFG: 364,852 euros
Duration: 32 months

Prof. Dr. Jörg Distler
ZAC-1 controls TGFß-dependent fibroblast activation in fibrotic diseases via regulation of the AP-1 signalling cascade
DFG: 253,600
Duration: 36 months
GRK5 as a multimodal regulator of GRK5 TGFß-dependent fibroblast activation in systemic sclerosis
DFG: 584,450
Duration: 36 months

Prof. Dr. Heiner Fangerau
Institute of History, Theory and Ethics of Medicine
Indexing and digitisation of pharmacy-historical questionnaires (1925-55) and correspondence in "Vester's Archive" for the Gemeinsame Normdatei (GND) (Common Standard File)
DFG: 309,930 euros
Duration: 36 months

Prof. Dr. Tanja Fehm
University Tumour Centre (UTZ)
Funding of the Centre for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD)
German Cancer Aid e.V.: 1,200,000
Duration: 48 months

Prof. Dr. Tanja Fehm
Department of Gynaecology
DETECT CTC: Application of liquid biopsies to decipher therapy resistance mechanisms and develop adaptive treatment strategies in metastatic breast cancer, SP 1, SP 5
German Cancer Aid e.V.: 361,062 Euro and 330,426 Euro
Duration: 36 months

PD Dr. Torsten Feldt
Department of Gastroenterology, Hepatology and Infectiology
Survey on knowledge and practices in livestock farming in anthrax-endemic areas for the development of a "Social and Behaviour Change Communi- cation" (SBCC) for the prevention of anthrax transmission in Ethiopia
DFG: 15,334 euros
Duration: 36 months

PD Dr. Torsten Feldt
Department of Gastroenterology, Hepatology and Infectiology
Clinical Partnerships - Partners Strengthen Health (Academic)
German Society for International Cooperation (GIZ) GmbH: 299,310 euros
Duration: 21 months

Prof. Dr. Jay Gopalakrishnan
Institute of Human Genetics
Glio-ORG: Development of a personalised in vitro invasion test for modelling the behaviour of brain tumours in patients for clinical therapy support and drug development
BMBF: 1,516,667 Euro
Duration: 36 months

Dr. Norman-Philipp Hoff
Clinic of Dermatology
KMU-innovativ - Joint project: Precise dermatological skin cancer diagnostics through AI and deep learning (Mole Vision) - Subproject: Integration and ethics
BMBF: 159,132 euros
Duration: 42 months

Prof. Dr. Marc Jacobsen
Department of General Paediatrics, Neonatology and Paediatric Cardiology
Non-tuberculous mycobacteria in patients with suspected pulmonary tuberculosis in Ghana - the role of environmental, pathogenic and host factors
DFG: 288,136 euros and 360,489 euros (Odame Phillips, Ghana)
Duration: 36 months

Prof. Dr. Nadja Kairies-Schwarz / Prof. Dr. Stefan Wilm
Institute of Health Services Research and Health Economics / Institute of General Medicine
DigIn2Perio - Digitally Integrated Care for Diabetes Mellitus Type 2 and Periodontitis
Federal G-BA: 186,036 euros (Kairies-Schwarz), 716,375 euros (Wilm)
Duration: 48 months

Prof. Dr. Philipp Lang
Institute of Molecular Medicine II
Changing the game: Next generation DNAzymes for antiviral therapies
Volkswagen Foundation: 181,600 euros (TP)
Duration: 36 months

Dr. Gabriel Leprivier
Institute of Neuropathology Characterisation of the functional and therapeutic relevance of 4EBP1 in medulloblastoma with oncogenic MYC activation
German Cancer Aid e.V.: 288,835 euros
Duration: 36 months

Prof. Dr. Günter Niegisch
Department of Urology
Synergistic effect of PARP inhibitors and bromodomain and extra-terminal motif (BET) inhibitors by inducing DNA repair deficiency (BRCAness) in urothelial carcinomas
Wilhelm Sander Foundation: 145,000 euros
Duration: 24 months

Prof. Dr. Tom Lüdde
Department of Gastroenterology, Hepatology and Infectiology
FUTURE-4-CSPPM: Shaping the Future for Clinician Scientists in Precision Metabolic Medicine
DFG: 2,843,300 euros
Duration: 36 months

Prof. Dr. Thomas Meißner
Department of General Paediatrics, Neonatology and Paediatric Cardiology
Al-PHCA - AI-based Health Care in Children and Adolescents - TP Empirical Studies and Law
BMBF: 360,174 euros
Duration: 41 months

Prof. Dr. Johannes Stegbauer
Department of Nephrology
Significance of alpha2A-adrenoceptors in renal inflammation and fibrosis
DFG: 289,957 euros
Duration: 36 months

Third-party funded projects 2022, 2nd quarter

Prof. Dr. Peter Angerer
Institute of Occupational, Social and Environmental Medicine
Home office during and after the SARS-Cov-2 pandemic: Supporting companies in the introduction and expansion of new arrangements
Federal Institute of Occupational Safety and Health: o.A.
Duration: since 04.01.2022

Dr. Thomas Beez
Clinic of Neurosurgery
Pediatric Craniectomy & Cranioplasty Registry (pedCCR), funding project no. 202013
Hannelore Kohl Foundation: 50,346 euros
Duration: 48 months

Dr. Dan Bieler
Clinic of Orthopaedics and Trauma Surgery LeAf
Trauma - Quality of life and ability to work after severe trauma
Innovation Committee at the G-BA: 275,559 Euros
Duration: 17 months

Prof. Dr. Felix Distelmaier
Department of General Paediatrics, Neonatology and Paediatric Cardiology
Analysis of the coenzyme Q10 biosynthesis metabolic pathway using metabolite profiling
DFG: 142,100 euros
Duration: 36 months

Prof. Dr. Margitta Elvers
Department of Vascular and Endovascular Surgery
Influence of the IL-6 signalling pathway on hepatic thrombopoietin formation, platelet turnover and platelet activation during acute inflammation
DFG: 564,400 euros
Duration: 36 months

Prof. Dr. Heiner Fangerau
Institute of History, Theory and Ethics of Medicine
Abuse of medicines in children and adolescents since the foundation of the state of North Rhine-Westphalia until 1980
Ministry of Labour, Health and Social Affairs NRW: 429,114 euros
Duration: 24 months

Prof. Dr. Heiner Fangerau
Institute of History, Theory and Ethics of Medicine
Neurology 1950-1995: The DGN and the Independence of German Neurology
German Society of Neurology: 110,000 euros
Duration: 36 months

Dr. Ute Fischer
Department of Paediatric Oncology, Haematology and Clinical Immunology
Analysis of risk factors for ETV6- RUNX1-positive childhood leukaemia and translation into preventive measures and interventions
German Cancer Aid e.V.: 203,535 euros
Duration: since 01.03.2022

Dr. Edgar Grinstein
Department of Haematology, Oncology and Clinical Immunology
The role of the factor nucleolin in the stem cell compartment in acute myeloid leukaemia
Leukaemia Lymphoma League e.V.: 49,960 euros
Duration: 24 months

Dr. André Karger
Clinical Institute of Psychosomatic Medicine and Psychotherapy
Professional guides in cancer counselling centres: Development and piloting of a complex intervention, CARES study
German Pension Insurance: 54,000 euros
Duration: 18 months

Dr. Sabrina Kastaun
Institute of General Medicine
OptiCor - Optimising the treatment of CHD by training GPs in brief counselling to increase physical activity
BMBF: 971,975 Euro
Duration: 36 months

Prof. Dr. Gesine Kögler
Institute of Transplantation Diagnostics and Cell Therapeutics (ITZ)
Horizon HLTH 2021 HEAL - Project #101056712
EU: 233,140 euros
Duration: 42 months

Dr. Sven Loosen
Department of Gastroenterology, Hepatology and Infectiology
Evaluation of circulating suPAR concentrations as an early predictor of complicated disease progression of infectious diseases for targeted patient stratification at first contact with the health care system in sub-Saharan Africa
HHU Foundation for Research into Infectious Immunological Diseases: 9,210 Euro
Duration: since 17.05.2022

Prof. Dr. Tobias Marschall / Prof. Dr. Dagmar Wieczorek / Prof. Dr. Arndt Borkhardt
Medical Biometry and Bioinformatics/ Human Genetics/ Paediatric Oncology, Haematology and Cl. Immunology
Genomic instability syndromes as a toolbox for deciphering novel DNA repair pathways
DFG: 94,600 euros / 36,250 euros / 36,250 euros
Duration: 36 months

Prof. Dr. Tobias Marschall
Institute of Medical Biometry and Bioinformatics
Network University Medicine: Second funding phase CODEX+
BMBF: 43,989 euros
Duration: 12 months

Dr. Alexandru-Emil Matei
Polyclinic and Functional Area of Rheumatology
EN1-targeting therapy for the treatment of fibrosis
Else Kröner-Fresenius Foundation: 229,480 euros
Duration: 16 months

Philipp Niklas Ostermann
Institute of Virology
lnvestigating the importance of cellular autophagy mechanisms on severe acute respiratory syndrome coronavirus 2 replication
HHU Foundation for Research into Infectious Immunological Diseases: 9,850 euros
Duration: since 17.05.2022

Dr. Max Prost
Department of Orthopaedics and Trauma Surgery
Sport-specific damage to the lumbar intervertebral disc in competitive golf: Prospective data analysis using biochemical sensitive MRI imaging
German Arthrosis Aid Association: 19,000 euros
Duration: since 22.06.2022

Prof. Dr. Marc Remke
Department of Paediatric Oncology, Haematology and Clinical Immunology
Synergistic targeting of MYC and mTOR in MYC-driven leukemia
Friedrich Spicker Foundation: 25,000 euros
Duration: 14 months

Prof. Dr. Marc Remke
Department of Paediatric Oncology, Haematology and Clinical Immunology
Project IVAC-AN
DKFZ: 55,101 euros
Duration: 18 months

Dr. Philipp Slotty
Department of Neurosurgery
Establishment of intraoperative neurophysiological monitoring during thermocoagulation of the ganglion
Gasseri Foundation of Research on Aging: 6,554 euros
Duration: 19 months

Prof. Dr. Jörg Timm
Institute of Virology
Determination of parameters relevant to the course of the SARSCoV-2 pandemic
Ministry of Labour, Health and Social Affairs NRW: 461,356 euros
Duration: 10 months

Prof. Dr. Bettina Westhoff
Clinic of Orthopaedics and Trauma Surgery LL-uCP - Diagnostics and Therapy of Unilateral Spastic Cerebral Palsy
BMBF: 68,813 euros
Duration: 18 months

Third-party funded projects, 1st quarter 2022

Prof. Dr. Peter Albers
Clinic for Urology
PRO-P - Influence of electronic Patient Reported Outcomes (ePROMS) in surgical therapy of prostate carcinoma on the postoperative course
Federal Government / G-BA: 2.393.100
Duration: 36 months

Prof. Dr. Peter Albers
Department of Urology
Risk-adapted prostate cancer (PCA) early detection through a baseline PSA determination in young men: Prostate Cancer Early Detection Intervention Study - PROBASE
German Cancer Aid e.V.: 902.647 euros
Duration: 24 months

Prof. Dr. Peter Albers
Department of Urology
Cancer Prevention - Graduate School - Risk consultation for men with a familial or hereditary predisposition to prostate cancer
German Cancer Aid e.V.: 257.159 euros
Duration: since 17.02.2022

Dr. Anna Kathrin Assmann
Department of Cardiac SurgeryCerebral perfusion during ante- and retrograde extracorporeal circulation in atherosclerotic rabbits
DFG: 80.890 euros
Duration: 12 months

Prof. Dr. Michael Bernhard
Central Emergency Department
Network University Medicine: Second funding phase
Federal Government / BMBF: 20.970 euros
Duration: 12 months

Prof. Dr. Arndt Borkhardt
Department of Paediatric Oncology, Haematology and Clinical Immunology
German Cancer Aid relief fund for relatives of cancer patients from Ukraine treated in Germany
German Cancer Aid e.V.: n.a.
Duration: since 17.03.

Prof. Dr. Simon Eickhoff
Institute of Systemic Neuroscience
Prediction of the treatment success of dialectical behavioural therapy
DFG: 74.250
Duration: 36 months

Prof. Dr. Tanja Fehm
Department of Obstetrics and Gynaecology
DETECT CTC: Application of liquid biopsies to decipher therapy resistance mechanisms and develop adaptive treatment strategies in metastatic breast cancer
German Cancer Aid e.V.: 2.000.000 euros
Duration: since 14.02.2022

Prof. Dr. Esther Florin
Institute of Clinical Neuroscience and Medical Psychology
Pain processing in Parkinson's disease: motivational versus sensory components
DFG: 326.263 euros
Duration: 36 months

Prof. Dr. Ulrich Germing/Prof. Dr. Norbert Gattermann
Department of Haematology, Oncology and Clinical Immunology
Mutation analyses for haematological and cardiological risk management in patients with clonal haematopoiesis of unclear significance (CHIP)
German Cancer Aid e.V.: 304.535 Euro
Duration: since 04.03.2022

Prof. Dr. Jay Gopalakrishnan
Institute of Human Genetics
3D brain organoids with eye-like structures for modelling early childhood retinal dystrophies
DFG: 258.800
Duration: 36 months

Dr. Daniel Hein
Department of Paediatric Oncology, Haematology and Clinical Immunology
Identification of risk factors and derivation of signalling pathway dependencies for ETV6-RUNX1+preleukaemia
DFG: 271.300 euros
Duration: 36 months

Dr. Björn-Erik Jensen
Department of Gastroenterology, Hepatology and Infectiology
EUCARE Horizon-HLTH-2021-Corona1
EU: n.a.
Duration: 60 months

Dr André Karger
Clinical Institute of Psychosomatic Medicine and Psychotherapy
KommRhein lnterpro - Effectiveness of a skill-oriented interprofessional communication training for ward units at organ cancer centres
German Cancer Aid e.V.: 12.467 euros
Duration: 6 months

Prof. Dr. Tobias Marschall
Institute of Medical Biometry and Bioinformatics
Network University Medicine Covid-19: Second funding phase
Federal Government / BMBF: 41.022 euros
Duration: 12 months

Prof. Dr. Tobias Marschall
Institute of Medical Biometry and Bioinformatics
Recovery Assistance for Cohesion and the Territories of Europe (REACT-EU)- Project Call "Digitalisation in Clinical Medical and Health Research (OnkoHPC)
EU: 1.507.730 Euro
Duration: 12 months

PD Dr Amin Polzin
Department of Cardiology, Pneumology and Angiology
Factor Xa inhibitors as regulators of proteome and function of platelets
DFG: 266.025 euros
Duration: 36 months

Dr. Nan Qin
Department of Paediatric Oncology, Haematology and Clinical Immunology
Targeting the long noncoding RNA OTX2-AS1 in pediatric medulloblastoma
German Childhood Cancer Foundation: 121.870 Euro
Duration: since 01.02.2022

Prof. Dr. Jürgen Scheller
Institute of Biochemistry and Molecular Biology II
Modularity and applications of synthetic cytokine receptors
DFG: 413.300 euros
Duration: 36 months

Prof. Dr. Stefanie Scheu
Institute of Medical Microbiology and Hospital Hygiene
Influence of plasmacytoid dendritic cell and dendritic cell precursor communication in bone marrow during sepsis-induced immune dysregulation
DFG: 226.725 euros
Duration: 36 months

Dr. Lars Schimmöller
Institute of Diagnostic and Interventional Radiology
Spectral diffusion analysis for the detection and classification of prostate carcinoma
DFG: 36.500 euros
Duration: 24 months

Prof. Dr. Johannes Siegrist
Institute of Medical Sociology
Psychosocial work and health - a new perspective
DFG: 38.240 euros
Duration: 24 months

Prof. Dr. Markus Uhrberg
Institute of Transplantation Diagnostics and Cell Therapeutics (ITZ)
Characterisation of the molecular identity and function of human ILC3 using a new in vitro differentiation platform
DFG: 381.550 euros
Duration: 36 months

Prof. Dr. Markus Uhrberg
Institute of Transplantation Diagnostics and Cell Therapeutics (ITZ)
Generation of tolerogenic CAR NK cells from haematopoietic progenitor cells for allogeneic tumour therapy
German Cancer Aid e.V.: 212.777 euros
Duration: since 01.03.2022

Dr. Mihael Vucur/Prof. Dr. Tom Lüdde
Department of Gastroenterology, Hepatology and Infectiology
Investigations into the molecular function of TAK1 as a key molecule in the development of pancreatic carcinoma
German Cancer Aid e.V.: 311.953 euros
Duration: since 10.03.2022

Prof. Dr. Sascha Weggen
Institute of Neuropathology
ADAMTS proteases in the pathogenesis of Alzheimer's disease
DFG: 242.490 euros
Duration: 36 months

Prof. Dr. Stefan Wilm
Institute of General Medicine (ifam)
Longitudinal Curriculum in General Medicine to Strengthen Family Medicine Care in Rural Regions (LOCALHERO)
Federal Government/ Federal Office of Administration Cologne: 228.863 euros
Duration: 36 months

Prof. Dr Hans-Jörg Wittsack
Institute of Diagnostic and Interventional Radiology
Spectral diffusion analysis for the detection and classification of prostate carcinoma
DFG: 201.250 euros
Duration: 24 months